| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 26/07/25 01.30 | New England Revolution | CF Montreal | 1:3 |
| Annullata | Houston Dynamo | Los Angeles Galaxy | -:- |
| 26/07/25 02.30 | FC Dallas | New York City FC | 3:4 |
| 26/07/25 02.40 | Columbus Crew | Orlando City | 1:3 |
| 26/07/25 04.30 | San Diego FC | Nashville SC | 1:0 |
| 26/07/25 04.30 | Los Angeles FC | Portland Timbers | 0:1 |
| 27/07/25 01.15 | Inter Miami CF | Cincinnati FC | 0:0 |
| 27/07/25 01.30 | Atlanta United FC | Seattle Sounders | 2:2 |
| 27/07/25 01.30 | Philadelphia Union | Colorado Rapids | 3:1 |
| 27/07/25 01.30 | D.C. United | Austin FC | 2:4 |
| 27/07/25 01.30 | Charlotte FC | Toronto FC | 2:0 |
| 27/07/25 02.30 | Chicago Fire | New York Red Bulls | 1:0 |
| 27/07/25 02.30 | St. Louis City SC | Minnesota United FC | 1:2 |
| 27/07/25 03.30 | Real Salt Lake | San Jose Earthquakes | 2:1 |
| 27/07/25 04.30 | Vancouver Whitecaps | Sporting Kansas City | 3:0 |